Today we’re talking about cannabis and epilepsy. Cannabis has been used as a treatment of seizures and epilepsy for millennia and many different cultures and most recently in the modern world and in modern medicine it’s been used to treat children with specific forms of childhood epilepsy who failed many many drugs to control their seizures.
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Partial Video Transcript:
So I’m gonna tell you a little bit about how we think cannabis and epilepsy work and the most common ways that it’s used so CBD oil and cannabis medicines are really gaining traction as a potential anti epileptic treatment for children with epileptic disorders in childhood seizure disorders especially who’ve not responded to conventional drugs and there’s been quite a few high-profile cases in the media of children who are trying to get access to cannabis because it’s helped them reduce their seizures quite considerably or in some cases even really have no seizures for periods of time after really trying every drug on the market and one of the mainstays of therapy when it comes to cannabis and seizure control or epilepsy is CBD or cannabidiol that’s because CBD has been quite well studied as far as the cannabis plant molecules for its anti seizure activity so it has the ability to reduce seizure activity increases your threshold in a number of animal models in preclinical trials and in many many cases with children who have these epilepsy disorders that are very difficult to treat especially one called your vet syndrome and another one called Lennox gastro syndrome so what are we actually talking about like what products are people actually using when it comes to treating epilepsy with cannabis well both hemp derived CBD oils and medical cannabis with a slightly higher amount of THC have been used to treat different types of epilepsy generally what you do especially with it flipsie is you start with a very very low THC very very high CBD oil so generally speaking that’s a CBD oil sometimes even from hemp that has less than 0.2 or 0.3 percent THC sometimes if you’re starting with a medical product you might start with something that’s slightly higher in THC potentially a 1% THC with 18 to 20 percent CBD so again we’re talking about very very high CBD low THC forms of oil how it potentially works in the brain to help decrease seizures by a number of mechanisms one of them seems to be by a g-protein coupled receptor one of them seems to be by a serotonin receptor mechanism one of them we think is about by it something called Avenel Lloyd receptor and many many more so we’re still really learning about why CBD can actually work for seizure control when other drugs fail on average children who resort to medical cannabis and CBD have tried an average of 10 different antiepileptic drugs before they try CBD so we’re talking about really this is a last resort treatment but it actually works very very well for a number of patients there’s another form of CBD that’s actually been made by some pharmaceutical companies and only contains CBD it’s what’s called it CBD islip medication versus a full-spectrum CBD oil that contains other parts of the plant and even in those studies many patients have responded positively ….
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